Analysis of Treatment Outcomes of Patients With Cystic Prolactinomas: Report of Four Cases

Abstract Background: Prolactinomas are the most common functional pituitary adenomas. Treatment with dopamine agonists is considered as first-line therapy. Cystic prolactinoma a variant prolactinoma. . It was assumed that since cystic area does not contain receptors, prolactinomas would respond to medical treatment. However, in recent years, it has been shown can also be treated agonists, and treatment become more preferred than surgical In this report, we aimed evaluate effectiveness of patients who medically our clinic. Materials methods: Twenty-nine were followed up hospital between 2019-2020 evaluated retrospectively. Four (13%) being for Radiological images, laboratory findings, records reviewed. Results: all women. The average age 36 years. 3 (75%) had menstrual irregularity, 2 (50%) galactorrhea, 1 patient (25%) headache at time admission. Tumor size regressed two tumor disappeared completely one patient. Although symptomatic improvement normalization prolactin achieved patients, lesion did shrink. We continued there no indication surgery. Discussion: There conflicting results literature regarding management prolactinomas. Recently, dopamin agonist therapy suggested first- line option A study reported male predominance cyst formation but observed female report. Faje et al. their study. Presentation different from solid And although very limited number which consistent literature.